Ralf,

it's not that uncommon. See for example:
http://www.rcsb.org/pdb/files/1ejg.pdb

Also, you may want to couple partially occupied residue's side chain with partially occupied water.

Pavel.


On 11/4/2008 9:36 AM, Ralf W. Grosse-Kunstleve wrote:
Hi Tassos,

  
However, I want to refine my MET residues in double conformations, one
as MET (AMET) and the other one as MSE (BMSE) with each 0.5 occupancy
to start with.
    

In addition to what Pavel wrote: I just tried out the AMET BMSE mix
without giving any manual atom selections, and it works fine for me.
(P.S.: I'm thrilled to see this use of the
multiple-conformers-with-mixed-residue-names feature,
since it was a lot of work.)

Ralf
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