Hello everyone,<br clear="all"><br><div>I have two data sets, one  for apo form and the other is co-crystalized with ligandl. Both data sets has P1211 space group; resolution is about ~3.5Angstrom.</div><div>Unit cell:</div>
<div>Apo:     105.22, 266.26, 110.63       90.00, 108.12, 90.00</div><div>Ligand: 104.60, 264.74, 109.98,      90.00, 106.33, 90.00  <br><br></div><div>When I try to create an isomorphous difference map using phenix GUI, an error message pops up: crystal symmetry mismatch between different files.</div>
<div>Anyone could tell me what&#39;s the problem and how to solve it? </div><div> <br><div>======================</div>Jason<div>Structural Biology Department</div><div>University of Pittsburgh</div><div>======================</div>
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