Re: [phenixbb] Refinement Problem

Date: Wed, 12 Jan 2011 17:12:04 -0500 (EST) From: Christopher W Davies To: [email protected] Subject: [phenixbb] Refinement Problem

I am having an issue with refining my structure. I have a 2.36 A resolution dataset. I have found a solution by molecular replacement in the space group P3221. I have been refining the structure, however, my Rfactor/Rfree are not decreasing even though I have good density. My current Rfactor/Rfree values are .40/.43. Can anyone help me?

Thanks.

Chris

Chris, there is a collection of things to think about at http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Refinement#R-fac... HTH, Kay