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10 Jul
2014
10 Jul
'14
5:03 p.m.
Charles, So if you have bound ligand with a covalently-linked Bromine, and the ligand isn't abundant in your unit cell, don't you *expect* the anomalous signal to be weak ? Have you tried a DANO model-phased difference map or something comparable ? Phil Jeffrey Princeton On 7/10/14 12:52 PM, CPMAS Chen wrote:
Well, let me make this clear.
1. I am using Br anomalous signal to identify the potentially bound ligand. 2. I do shoot the crystals at 0.92A. 3. the different crystals have different resolution, but anomalous signal was weak as reported by autoxds.
Charles