I was wondering when you would want to change multi_body_factor= 1?  Is this something you would change when you have multiple rigid body domains?  From the name, that's what I'm guessing it's for.  I'm refining a large over 400 kD multimer complex with two complexes in the ASU.  So, if I have 5 chains in each multimer would I want to try to change the multi_body_factor to 10?  Or does multi_body_factor affect something else.