On Mon, 2010-05-17 at 17:37 -0400, Phil Jeffrey wrote:
Demonstrate that the way that phenix.refine, as currently implemented, inappropriately throws away weak data is never potentially deleterious to the quality of a protein structure model.
Phil, I have always used denzo/scalepack, and then scalepack2mtz to convert .sca file to .mtz file. So my data is always processed according to French&Wilson. Now from what you are saying I understand that there is some possibility to get into using non-truncated data with phenix? And not only that, it seems to be the default? I suspect that French&Wilson statistics is actually applied by phenix internally if the supplied mtz-file only has intensities. If that is not the case, the problem is more serious than I thought. Otherwise it would take deliberate user effort to get into trouble, since TRUNCATE=YES is the default of the corresponding CCP4 program. Ed. -- "I'd jump in myself, if I weren't so good at whistling." Julian, King of Lemurs