On 27 Aug 2008, at 04:37, Pavel Afonine wrote:
I'm not sure I understand why you don't want to use your original file
with reflections...
As a fact, I have a question to the all community... why would people refine against reflections different that the "true" ones, e.g. the ones obtained directly after indexing? My thought was that if one tries to refine against, let say, modified reflections, it will result with model bias, and "wrong" interpretation of the data. At least, this is what I'm telling my students: ALWAYS refine against your ORIGINAL reflections!
Am I missing something there?
Kind regards.
-- Leo --
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Chavas Leonard, Ph.D. @ Osaka, Japan
Research Associate
Marie Curie Actions Fellow
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Faculty of Life Sciences
The University of Manchester
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Tel: +44(0)161-275-1586
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