The resolution is 2.5 A.� The wilson B is about 50.� I know B factor of the backbone is lower than that of the sidechian.� But a B factor like 4 is definitely wrong.

Jianghai


On Dec 14, 2006, at 12:11 PM, Peter Zwart wrote:


4) The refinement (TLS + ML + B individual) went through, I got
reasonable R, Rfree, rmsdBOND, rmsdANGLE.But the B factors are
pretty low.The B factor of the backbone is much lower than the side
chain, some have numbers like 4.Some metal atoms also have B
factors around 4.What did I do wrong?

What is the resolution of your data?

Backbone B-s usually are lower than the main chain.

What is the Wilson B value reported by phenix.refine?
You could re-refine and randomize all B-values and see what happens (I
have to get back to you to to get the exact command for this). Maybe it
is useful to obtain a copy of the latest verison of phenix.refine by
downloading cci_apps from our server http://www.phenix-online.org.


If your B-values still come out lowish, try growing crystals that do not
diffract very well, that usually does the trick.

HTH

Peter








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