Re: [phenixbb] is derivative data useful for looking for the missing part of the model?

Thanks so much!It looks promising. If I have two or more derivative data and want to combine all these information. Can I just do MRSAD individually for each dataset, and combine them? 引用 Nathaniel Echols ：

On Tue, Jun 15, 2010 at 4:03 PM, Francis E Reyes

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Using the model to find the heavy atom sites and then calculating phases on those sites (without model) might help. ( I believe phenix will output a phase combined map (model + experimental phases)).

Correct, this is the default behavior if you provide a model directly to AutoSol (or Phaser). There is however a semi-automatic way to use the model phases to find sites without biasing the experimental map; see the documentation here:

https://www.phenix-online.org/version_docs/1.6.2-432/autosol.htm#anch126

(The AutoBuild step is optional - you could just look at the density-modified map after AutoSol is done.)

-Nat