Dear All,
 
The default value of the starting temperature of Phenix refine simulated annealing is 5000. At this temperature all the protein structure will be destroyed.
 
Will you please explain why we start the simulated annealing at 5000? Will you please explain to me the basic theory of the Phenix refine simulated annealing or tell me a link on the introduction of Phenix refine simulated annealing?
 
I am looking forward to getting your reply.
 
Cheers,
 
Dialing