Raja

Actually I used 3 letter code for nucleotides in PHENIX refinement. Before submission to PDB I changed to DA, DC ....like this. Otherwise PDB deposition system can not recognize. Might be there is a way, so that I can avoid this hassle of changing this code for PDB deposition. Please tell me if I did anything wrong.
Thanks...
  
This is very interesting.  In my previous email, I had mixed up the codes AD, CD, GD, TD that the monomer library uses and the standard codes that PDB uses, DA, DC, ...  Ralf tells me that phenix.refine recognises these latter codes so there is something else up with the refinement.

You should follow Pavel's advice and check the .geo file.  It certainly seems like the refinement has not converged.

Nigel
Raja 

----- Original Message -----
From: Nigel W Moriarty <[email protected]>
Date: Sunday, May 2, 2010 9:43 am
Subject: Re: [phenixbb] Error in PDB Validation letter
To: PHENIX user mailing list <[email protected]>

  
Raja

Regarding the BML compound. This code is already taken for 4-
BROMOPHENOL.  You can look at it using

phenix.reel --chemical-components=BML

You can generate a new unused code thus

elbow.get_new_ligand_code

and one being with B thus

elbow.get_new_ligand_code B

Then the PDB with not compare you compound with the one currently 
known as BML.

Regarding the deviations.  The nucleotides denoted as DA, DC, DT, 
... are not using the standard codes.  This may mean that you 
generated new restraints that are not as accurate as the standard 
set in the restraints library.  Either way, I suggest renaming the 
residues to the standard codes and re-refining.  This will use the 
standard restraints and will likely approach the values mandated by 
the PDB.

Nigel

On 4/30/10 12:37 PM, Raja Dey wrote:
    
Hi,
   I am getting two errors in pdb validation report as follows:
I think I need to use B-DNA constraint in the refinement. This is 
      
a 2.4 A data. How can I do that in PHENIX in cammand line promt.
    
Another thing is, I have a small molecule in the complex, which I 
      
called as BML. I think that's might be the problem. This is known 
as BML210. What I should call this compound? Should I also give a 
chain ID for this compound? See the errors given below.
    
   *** Covalent Angle Values:

   The overall RMS deviation for covalent angles relative to the 
      
standard     dictionary is    1.4 degrees.
    
   The following table contains a list of the covalent bond angles
   greater than 6 times standard deviation.


Deviation  Residue  Chain  Sequence  AT1  -  AT2  -  AT3    Bond  
      
 Dictionary  Standard
    
            Name     ID     Number                          Angle 
      
    Value    Deviation
    
-------------------------------------------------------------------
      
------------------------
    
   -4.8     DA       E        1      C1'  -  C2'  -  C3'     97.6 
      
   102.4        0.8
    
   -5.8     DA       E        2      C1'  -  C2'  -  C3'     96.6 
      
   102.4        0.8
    
    3.3     DA       E        2      N9   -  C1'  -  O4'    111.6 
      
   108.3        0.3
    
   -5.0     DC       E        5      N1   -  C1'  -  O4'    103.0 
      
   108.0        0.7
    
   -5.1     DT       E        6      C1'  -  C2'  -  C3'     97.3 
      
   102.4        0.8
    
   -6.7     DT       E        8      C1'  -  O4'  -  C4'    103.4 
      
   110.1        1.0
    
    2.3     DT       E        8      N1   -  C1'  -  O4'    110.6 
      
   108.3        0.3
    
   -4.5     DT       E       11      N1   -  C1'  -  O4'    103.5 
      
   108.0        0.7
    
   -6.1     DA       F        2      C1'  -  C2'  -  C3'     96.3 
      
   102.4        0.8
    
    3.0     DA       F        2      N9   -  C1'  -  O4'    111.3 
      
   108.3        0.3
    
   -5.3     DC       F        5      N1   -  C1'  -  O4'    102.7 
      
   108.0        0.7
    
   -4.9     DT       F        6      C1'  -  C2'  -  C3'     97.5 
      
   102.4        0.8
    
   -4.5     DA       F       10      N9   -  C1'  -  O4'    103.5 
      
   108.0        0.7
    
   -7.8     DA       F       11      N9   -  C1'  -  O4'    100.2 
      
   108.0        0.7
    

==> The following residues have extra atoms:                       
      
          RES MOD#C SEQ          ATOMS
    
        BML(      100)          N1  C10  C11  C12  C13  C14  C15  
      
C16  C17  C18                             C19   O2   N2  C20   N3   
C7   C8   C9 
    

ERROR: dissociated residue(s):
	BML  100


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-- 
Nigel W. Moriarty
Building 64R0246B, Physical Biosciences Division
Lawrence Berkeley National Laboratory
Berkeley, CA 94720-8235
Phone : 510-486-5709     Email : [email protected]
Fax   : 510-486-5909     Web   : CCI.LBL.gov

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-- 
Nigel W. Moriarty
Building 64R0246B, Physical Biosciences Division
Lawrence Berkeley National Laboratory
Berkeley, CA 94720-8235
Phone : 510-486-5709     Email : [email protected]
Fax   : 510-486-5909     Web   : CCI.LBL.gov