Hi Stephen,
I don't know of any phenix tools that will average two maps, though you are right that everything is there to do it quite easily.
-Tom

On Mar 10, 2011, at 10:15 AM, Stephen Graham wrote:

Hi there,

I'd like to average 2Fo-Fc maps from 2 (approximately) isomorphous
data sets (one with ligand, one without) to see whether I get better
density for some of the noisier bits of the structure.  I don't want
to do any kind of solvent flattening, histogram matching, cyclical
averaging, etc; I just want to sum the equivalent pixels and divide by
2.

Is it possible to do this easily using any of the phenix tools?  It
seems like all the required plumbing is there with get_cc_mtz_mtz or
superpose_maps, but I can't find a phenix utility for averaging two
superposed maps.

Thanks,

Stephen

--
Dr Stephen Graham
1851 Research Fellow
Cambridge Institute for Medical Research
Wellcome Trust/MRC Building
Addenbrooke's Hospital, Hills Road
Cambridge, CB2 0XY, UK
Phone: +44 1223 762 638
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Thomas C. Terwilliger
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Los Alamos National Laboratory
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