Dear all I have a crystal that diffracted to about 3.5 A for the first 5 degrees and rapidly decayed after that. With xia2, I can get a good dataset to 6 A (CC1/2, I/sigma etc.) using all the frames. I can also process the first good frames with obviously low completeness (20%). As I only want to check if molecular replacement can be done before investing time on experimental phasing (not expecting miracles here and not publishing this yet), should I bother running Phaser? The closest search model only covers about 20 % of the protein with 20 % identity. Thanks.