Hi, I am trying to refine a couple of waters in a structure anisotropically in the latest version of CCI-Apps (Feb-08) . The selection is: refine.adp.anisotropic = "chain W and (resid 25 or resid 54)" The refinement works fine if "main.ordered_solvent = False". When I enable "main.ordered_solvent" the refinement fails with: "Sorry: Bad (empty or mixed) selection in adp_individual.aniso" during the first update of the solvent in macrocycle 1. A workaround is easy to implement, but I think this kind of scheme should work. Although it has all kinds of tricky implication for the downstream handling of the selection if the residues/waters in questions are deleted.... Cheers, Carsten