Hi Pavel, Thank you so much for providing the information and sharing the link. It was indeed useful. It helped a lot. I am now able to do so. Thanks Abhishek *________________________________________________* *Abhishek Suman* *Research Scholar, PhD* C/o, Dr. Rajakumara Eerappa Macromolecular Structural Biology Group Department of Biotechnology R# 517,315, Academic Block - A Indian Institute of Technology Hyderabad Kandi 502 285 Sangareddy Telangana INDIA Contact: +91 91002 74548 (O) +91 80843 11898 (R) Email: [email protected] ----------------------------------------------------------------- *Please don't print this e-mail or attachment unless necessary. Preserve trees on the planet.* On Wed, Jun 19, 2019 at 10:13 PM Pavel Afonine wrote:

Hi Abhishek,

I'm confident you can do it, and it is explained to some degree here:

"13 typical occupancy refinement scenarios and available options in phenix.refine" http://phenix-online.org/newsletter/

In the GUI it should be straightforward, if not please come back to us with *specific* questions.

Pavel

On 6/18/19 23:48, ABHISHEK SUMAN wrote:

Hello All,

I am solving a X-ray crystal structure of protein-DNA complex at 2.3 Angs. In my structure, it seems like the the duplex DNA is bound in two different conformations, and both the conformations are occupied in same density. I wish to know how to refine the alternative conformations of the DNA duplex in Phenix. In am using Phenix GUI.

Thanks Abhishek

*______________________________________________ *

*Abhishek Suman*

*Research Scholar, PhD*

C/o, Dr. Rajakumara Eerappa

Macromolecular Structural Biology Group

Department of Biotechnology

R# 517,315, Academic Block - A

Indian Institute of Technology Hyderabad

Kandi 502 285 Sangareddy

Telangana INDIA

Contact: +91 91002 74548 (O)

+91 80843 11898 (R)

Email: [email protected] -----------------------------------------------------------------

*Please don't print this e-mail or attachment unless necessary. Preserve trees on the planet.*

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