Hi Gabriela, You can use resolve NCS averaging in this case. The NCS in resolve tries to make the different copies agree to an extent that depends on their current individual agreement, so that the copies that are not so similar will not contribute as much as those that agree better (this is true as long as you do not specify "equal_ncs_weight" or "perfect_ncs" in resolve). If I understand you correctly, this variable weighting of NCS copies is what you may want. You can get this by running phenix.autobuild with your input PDB file, data file, sequence file as usual, and the keyword "maps_only=True" so that it just calculates a density-modified map and stops. All the best, Tom T

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Hi dear Phenixbb,

Is there a command tool to make ncs density averaging in a high oligomerization model that has some maps clearer than others? not multi-crystal but the same crystal.

Thank you,

Gabriela

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