Dear XDS users, the latest binaries of the XDS package are available for academic users from the “downloading” link at https://xds.mr.mpg.de/ . As the linked “Release Notes” indicate, a few changes were made to output formats, and the requirement for a dynamic library (libquadmath.so), which is not installed by default in most Linux distributions, was eliminated. If you are already running BUILT=20250714, there is no reason to upgrade. In addition to the routine testing against specific datasets performed by Wolfgang Kabsch and me for new XDS packages, this one was tested against a larger database of datasets put together by Clemens Vonrhein and Gerard Bricogne (Global Phasing), who also devised a range of analysis and display tools. A procedure for comparing this and future XDS packages against earlier ones, using a further expanded database, is being implemented in the “XDS reproducibility project” that was convened by Max Burian (Dectris) and is hosted in the Dectris Cloud. Besides the five people mentioned, Camilla Larsen (Dectris), Gleb Bourenkov (EMBL Hamburg) and Ashwin Chari (Max Planck Institute for Multidisciplinary Sciences, Göttingen) are contributing to this project. We expect this effort will ensure the reliability of the XDS package, improve its usage, and enhance the resulting data quality. Best wishes, Kay
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Kay Diederichs