Dear Karolina, I’ve just run a test with the current stable release and a fresh hhr file from HHpred, and it seems to be working for me. (On the other hand, the option to query the HHpred server from within the GUI seems to be broken; I think the site at the MPI has been reorganised since this was written, so we’ll have to look at that.) There was a brief period when, if you clicked the “HHR file” button, the file was saved without the .hhr extension, though that has since been fixed. If I use a file without the extension, then indeed MRage pops up an error saying “Unknown homology search file”. Could that be the problem you’re facing? If not, would it be possible for you to share (off-list) the files needed to reproduce the problem? Thanks for reporting it! Best wishes, Randy Read ----- Randy J. Read Department of Haematology, University of Cambridge Cambridge Institute for Medical Research Tel: +44 1223 336500 The Keith Peters Building Fax: +44 1223 336827 Hills Road E-mail: [email protected] Cambridge CB2 0XY, U.K. www-structmed.cimr.cam.ac.uk

On 12 Apr 2019, at 21:57, Karolina Michalska wrote:

Hi,

I've been trying to run MRage with an hhr file from HHPred, without much success. Phenix claims it does not recognize my hhr file. This is in the latest official release, I've tried older versions with the same outcome.

I'll appreciate your help.

Karolina

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