Hi Mark, Billy can say more, but my understanding is that this is a MacOS issue - there appears to be a time limit on graphical installers, that is often exceeded on older Macs. It is unclear if we can fix this as it looks like a hardcoded limit. Billy has been looking at. For the moment we have to recommend using the command line installers. Cheers, Paul

On Jun 7, 2026, at 1:06 AM, Mark Saper wrote:

I have an Intel MacBook Pro running macOS 15.7.7. I downloaded the appropriate GUI installer for Phenix 2.1. The installation runs for about 15 min and then fails with a vague message. This happened to me previously with Phenix 2.0. I used the command line installer in each case and that was successful. I reported the problem but I received no response. Can the GUI installers be fixed?

Thanks, Mark _____________________ Mark A. Saper, Ph.D. Visiting Professor Dept of Microbiology and Molecular Genetics Hebrew University Faculty of Medicine

Associate Professor Emeritus of Biological Chemistry University of Michigan Medical School

[email protected] mailto:[email protected] | +972 52 815-0480

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-- Paul Adams (he/him/his) Associate Laboratory Director for Biosciences, LBL (https://biosciences.lbl.gov) Principal Investigator, Computational Crystallography Initiative, LBL (http://cci.lbl.gov) Vice President for Technology, the Joint BioEnergy Institute (http://www.jbei.org) Principal Investigator, ALS-ENABLE, Advanced Light Source (http://als-enable.lbl.gov) Adjunct Professor, Department of Bioengineering, UC Berkeley (http://bioeng.berkeley.edu) Member of the Graduate Group in Comparative Biochemistry, UC Berkeley (http://compbiochem.berkeley.edu) Building 91, Room 410 Building 978, Room 4126 Tel: 1-510-486-4225 http://cci.lbl.gov/paul ORCID: 0000-0001-9333-8219 Lawrence Berkeley Laboratory 1 Cyclotron Road BLDG 91R0183 Berkeley, CA 94720, USA. Executive Assistant: Michael Espinosa [ [email protected] ][ 1-510-333-6788 ] Phenix Consortium: Ashley Dawn [ [email protected] ][ 1-510-486-5455 ] --