[phenixbb] Average maps (*not* NCS averaging)

Phil Jeffrey pjeffrey at princeton.edu
Thu Mar 10 09:29:23 PST 2011


I believe that the Uppsala program COMAP will do what you want, assuming 
you have maps in CCP4 format.  It's part of the Uppsala averaging suite.

Phil Jeffrey

On 3/10/11 12:15 PM, Stephen Graham wrote:
> Hi there,
> I'd like to average 2Fo-Fc maps from 2 (approximately) isomorphous
> data sets (one with ligand, one without) to see whether I get better
> density for some of the noisier bits of the structure.  I don't want
> to do any kind of solvent flattening, histogram matching, cyclical
> averaging, etc; I just want to sum the equivalent pixels and divide by
> 2.
> Is it possible to do this easily using any of the phenix tools?  It
> seems like all the required plumbing is there with get_cc_mtz_mtz or
> superpose_maps, but I can't find a phenix utility for averaging two
> superposed maps.
> Thanks,
> Stephen

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