[phenixbb] Average maps (*not* NCS averaging)

Frank von Delft frank.vondelft at sgc.ox.ac.uk
Fri Mar 11 00:14:03 PST 2011

I'm not sure this is a particularly rigorous way to get "noisier bits" 
less noisy.  Surely the way to do it is to refine one model using the 
other model as restraints.  Both refmac and buster do it, (maybe 
phenix.refine too).


On 10/03/2011 17:15, Stephen Graham wrote:
> Hi there,
> I'd like to average 2Fo-Fc maps from 2 (approximately) isomorphous
> data sets (one with ligand, one without) to see whether I get better
> density for some of the noisier bits of the structure.  I don't want
> to do any kind of solvent flattening, histogram matching, cyclical
> averaging, etc; I just want to sum the equivalent pixels and divide by
> 2.
> Is it possible to do this easily using any of the phenix tools?  It
> seems like all the required plumbing is there with get_cc_mtz_mtz or
> superpose_maps, but I can't find a phenix utility for averaging two
> superposed maps.
> Thanks,
> Stephen

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