[phenixbb] free R test or work set flag value

Andrew Purkiss-Trew Andrew.Purkiss-Trew at cancer.org.uk
Thu Mar 24 13:06:06 PDT 2011

>> On Wed, Mar 23, 2011 at 11:15 AM, Bryan Lepore <bryanlepore at gmail.com> wrote:
>>> i see:
>>> Test (R-free flags) flag value: 1
>>> is the work set the negation?
>> I'm not sure I understand the question,
> test =1
> work = anything except for 1
>>  but the work set (when assigned by Phenix) is 0.
> then if the test set has numbers other than 1 or 0 (e.g. from ccp4 -
> see link below) i take this to mean they are neither work nor free
> (i.e. Kleywegt's R_sleep) ... IIUC....

No, because the CCP4 (and from memory CNS was similar) method originally split the data into n equal sized groups and assigned each group a number from 1-n. So the Free set had the flag set to 1 and the other (n-1) values formed the working set. As explained in the link, these different sets (20 sets for a 5% Rfree group) were used for validation in density modification methods.

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