[phenixbb] Research Associate (Fixed Term) at the MRC Mitochondrial Biology Unit, University of Cambridge
jjr at mrc-mbu.cam.ac.uk
Wed May 15 02:32:01 PDT 2019
Posting on behalf of Dr Edmund Kunji:
The University of Cambridge wishes to appoint a Postdoctoral scientist
to join the research group of Dr Edmund Kunji in the MRC Mitochondrial
Biology Unit of the University of Cambridge.
The postholder will work within a programme focussed on mitochondrial
transporters. Transport processes are crucial for the functioning of
mitochondria and mutations in transport proteins cause of a wide range
of metabolic, neuromuscular and developmental diseases. Basic molecular
understanding of their structure and mechanism is required to understand
their role in health and disease.
The goal of the project is to study their structures in different
conformational states by electron cryo-microscopy and/or x-ray
crystallography. The post-holder will participate in every stage of the
process, from the generation of expression strains or cell lines,
isolation of mitochondria, purification and sample preparation, data
acquisition and processing, and structure model building and
interpretation. There will also be an opportunity to study their role
and mechanism using a wide range of biochemical and biophysical
techniques. This project is part of a collaborative SNF Sinergia grant
together with Profs. Hediger and Lochner of the University of Bern.
Candidates will have a PhD in Structural Biology/Biophysics or related
disciplines, and a track record of research achievements. Knowledge of
protein purification and experience in structural biology are essential.
Further details about the job may be found here:
The MRC Mitochondrial Biology Unit is a world-renowned centre for
mitochondrial research. Additional information can be found at
Fixed-term: The funds for this post are available for 3 years in the
The closing date for applications is Wednesday 12th June 2019 with
interview date yet to be confirmed.
Informal enquiries may be made to Dr Edmund Kunji (ek at mrc-mbu.cam.ac.uk).
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