[phenixbb] alpha-Fold 2?

[Jim Fairman]

For the most challenging proteins, AlphaFold scored a median of 87, 25
points above the next best predictions.* It even excelled at solving
structures of proteins that sit wedged in cell membranes, which are central
to many human diseases but notoriously difficult to solve with x-ray
crystallography.* Venki Ramakrishnan, a structural biologist at the Medical
Research Council Laboratory of Molecular Biology, calls the result “a
stunning advance on the protein folding problem.”

Source:
https://www.sciencemag.org/news/2020/11/game-has-changed-ai-triumphs-solving-protein-structures
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Jim Fairman
C: 1-240-479-6575


On Mon, Nov 30, 2020 at 10:25 AM lbetts0508 <laurie.betts0508 at gmail.com>
wrote:

> all - I just read the blurb in Nature Briefing about the DeepMind AI
> having made a big advance in the CASP protein fold prediction.
>
> Does it sound really transformational, does it work for membrane proteins
> - all the usual questions come to mind.
>
> Do we know enough yet about it?
>
> Signed an old protein crystallographer, L. Betts
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