[phenixbb] PhD position (Denmark), Structural biology with a focus on metabolite uptake

Bjørn Panyella Pedersen bpp at mbg.au.dk
Wed Jun 30 23:50:56 PDT 2021


Dear colleagues,
Please pass this open PhD position along to anyone who might be interested. Thanks!
jobRxiv link: https://bit.ly/3Ak5Far

All the best,
/Bjørn


STRUCTURAL AND FUNCTIONAL STUDIES of eukaryotic membrane proteins involved in metabolite transport

A PhD position is available in membrane protein biochemistry and structural biology in the research group of Dr. Bjørn P Pedersen at the Department of Molecular Biology and Genetics, Aarhus University, Denmark. The group studies the structure-function relationship of membrane proteins involved in metabolite uptake, primarily sterol and sugar uptake, as well as their regulation from a structural perspective (see http://pedersenlab.dk).

The PhD project will be developed in discussion with the selected candidate, but will involve expression, purification and structural/functional characterization of membrane proteins involved in metabolite uptake. Example see https://pubmed.ncbi.nlm.nih.gov/31543266/.

Structures are determined by cryo-electron microscopy, cryo-electron tomography and X-ray diffraction. This also involves expression and purification of membrane proteins, or complexes, use of detergents, and nanodiscs, and assays of transport in vesicles and in cells. First rate facilities are available in a highly cooperative environment.

The project is fully funded by the European Research Council (ERC). It would ideally suit an outstanding biochemistry graduate with a strong interest in structural biology. The candidate should have molecular biology, protein production and purification experience. Experience with membrane proteins or protein structure determination will be an advantage. Full training will be provided in all necessary areas of protein biochemistry and structural biology. Good English language skills are essential. Salary will be according to the collective agreement between the Danish Confederation of Professional Associations and the Danish State. The position will be filled as soon as a suitable candidate is identified, but start date is negotiable.

Applicant should send a CV, cover letter and names of two referees to Dr. Bjorn P Pedersen (bpp at mbg.au.dk). Deadline is July 31st 2021.

The city
In Aarhus you have easy access to beautiful nature and an exciting culture and city life that make Aarhus a wonderful place to live and work. See https://international.au.dk/life/locations/ for further details on the city and the university.
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