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<div class="moz-cite-prefix">Hi Felix,<br>
<br>
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<div>Hi Pavel</div>
According to your mail from yesterday I wonder how can I treat
Ramachandran outliers in very large molecules (close to 9000
residues). </blockquote>
<br>
- fix them manually first and then run refinement;<br>
- if after refinement some of them come back as outliers then you
consider them for including into Ramachandran restraints.<br>
<br>
Ramachandran restraints are good at keeping correct conformation
from becoming an outlier (due to poor density for instance), and NOT
for fixing wrong one.<br>
<br>
Pavel<br>
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