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Dear all,</div>
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We have a position available at the Francis Crick Institute - please share with any soon-to-finish PhD students and postdocs who might be interested:</div>
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<div class="ContentPasted0">We seek a talented, highly motivated and independent post-doctoral project research scientist to work on a project to design protein kinase C beta selective inhibitors for B cell malignancies. Work will be carried out in Neil McDonald's
laboratory at the Francis Crick Institute, in collaboration with clinician-scientist Ingo Ringshausen at the University of Cambridge, and is funded by a Cancer Research Horizon Therapeutic Catalyst Award.</div>
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<div class="ContentPasted0">The project will be funded for 18 months in the first instance, with the potential for extension depending on progress.
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<div class="ContentPasted0">The project will build upon prior work within our laboratory to characterise and develop new, selective kinase inhibitors. The work will involve both optimisation of existing inhibitors, and the parallel discovery of novel inhibitors
using an XChem Fragment screening approach at Diamond Light Source. </div>
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<div class="ContentPasted0">The Francis Crick Institute is situated in central London, and is the largest single-site biomedical research institute in Europe, with excellent provision for X-ray crystallography and medicinal chemistry to allow rapid characterisation
and follow-up of any lead compounds.</div>
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<div class="ContentPasted0">Prior experience with baculovirus protein expression and X-ray crystallography would be advantageous.
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<div class="ContentPasted0">Informal enquiries can be made to Professor Neil McDonald (neil.mcdonald@crick.ac.uk).
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<div class="ContentPasted0">Application Deadline: 1st Sept 2023.</div>
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<div class="ContentPasted0">For more details about the role and the application process, please see:</div>
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<a href="https://crick.wd3.myworkdayjobs.com/External/job/London/Postdoctoral-Project-Research-Scientist---Signalling-and-Structural-Laboratory_R1245-1" id="LPlnk924749">https://crick.wd3.myworkdayjobs.com/External/job/London/Postdoctoral-Project-Research-Scientist---Signalling-and-Structural-Laboratory_R1245-1</a><br>
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<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;"><b>Dr David C. Briggs CSci MRSB
</b></span><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;"><i>(he/him)</i></span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;">Principal Laboratory Research Scientist</span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;">Signalling and Structural Biology Lab</span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;">The Francis Crick Institute</span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;">London, UK</span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;"><i>Working hours: Mon-Fri 0900-1700</i></span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;">==</span></p>
<p style="margin-top:0px; margin-bottom:0px; margin-top:0; margin-bottom:0"><span style="font-family: "Trebuchet MS", Trebuchet, sans-serif; font-size: 10pt;"><a href="https://about.me/david_briggs" title="https://about.me/david_briggs" data-loopstyle="linkonly">about.me/david_briggs</a> |
<a href="https://orcid.org/0000-0002-9793-7339" title="https://orcid.org/0000-0002-9793-7339" data-loopstyle="linkonly">
OrcID</a> | <a href="https://scholar.google.co.uk/citations?user=DRKG5KwAAAAJ" title="https://scholar.google.co.uk/citations?user=DRKG5KwAAAAJ" data-loopstyle="linkonly">
Google Scholar </a></span></p>
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The Francis Crick Institute Limited is a registered charity in England and Wales no. 1140062 and a company registered in England and Wales no. 06885462, with its registered office at 1 Midland Road London NW1 1AT</p>
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