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<p>Hello,</p>
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<p>Coot has a feature called "find un-modeled blobs" to do this interactively, but it won't suggest what could go in the blobs so you still have to figure it out from all things present in your buffer.<br>
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<p>I don't know if phenix has a program for this.<br>
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<p>I hope this helps,<br>
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<p>Guillaume</p>
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<div id="divRplyFwdMsg" dir="ltr"><font face="Calibri, sans-serif" style="font-size:11pt" color="#000000"><b>From:</b> phenixbb-bounces@phenix-online.org <phenixbb-bounces@phenix-online.org> on behalf of Dmitry Semchonok <semchonok@gmail.com><br>
<b>Sent:</b> Sunday, December 17, 2023 7:34:50 PM<br>
<b>To:</b> Phenix email list <br>
<b>Subject:</b> [phenixbb] unassigned densities</font>
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<p class="elementToProof" style="margin-top: 0px; margin-bottom: 0px;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Dear colleagues, </span></p>
<p class="elementToProof" style="margin-top: 0px; margin-bottom: 0px;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);"><br>
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<p style="margin: 0cm 0cm 8pt;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Is there a way to assign cryo-EM densities not included in the model sequence? </span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Do you have any tools that can help? </span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">More closely, is there a way to screen the cryo-EM map + model, point out the unassigned densities, and provide the
possible structures to fit in (e.g., water molecules, etc.)? </span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);"> </span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Thank you.</span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);"><br>
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<p style="margin: 0cm 0cm 8pt;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Kind regards, </span></p>
<p style="margin: 0cm 0cm 8pt;" class="elementToProof"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);">Dmitry </span></p>
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