14 Nov
2014
14 Nov
'14
11:28 p.m.
On Fri, Nov 14, 2014 at 2:06 PM, Dale Tronrud
You also asked if burning your crystals could improve the map. If you have more crystals I would recommend soaking them in a higher concentration of ligand. No amount of fancy data collection is going to make the density of a low occupancy compound stronger. Getting the occupancy up will do you worlds of good.
But won't measuring the weak high-resolution reflections as accurately as possible help resolve map details like partial-occupancy atoms? (Although I think it's better to do this by collecting more redundant data than increasing the exposure time.) -Nat