Postdoctoral position open at the University of Massachusetts Medical School, in the Korostelev Lab: https://www.umassmed.edu/korostelev-lab/. We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome's central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some lab publications are provided below. Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: https://www.umassmed.edu/rti/about-the-rti/faculty-members/. Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development. We seek a highly motivated person who very recently received a PhD, or will soon receive a PhD. Applications sent prior to the dissertation defense date are welcome. Please submit the following information via email to: [email protected] 1) your CV (including publication list); 2) in less than 2 pages, an outline of your: (i) previous work - focusing on your most interesting finding(s); (ii) your current/future scientific interests, and whether/which aspects of translation regulation sound interesting to you; 3) email addresses of three references. Selected publications (accessible via the provided links): - Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation terminationhttps://elifesciences.org/articles/46850”. eLife.2019. - Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelityhttps://www.nature.com/articles/nature22397”. Nature. 2017. - Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunithttps://elifesciences.org/articles/28560”. eLife. 2017. - Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosomehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896748/”. eLife. 2016. - Loveland et al. “Ribosome•RelA structures reveal the mechanism of stringent response activationhttps://elifesciences.org/articles/17029”. eLife. 2016. --- Anna Loveland, Ph.D. [email protected] 617 610 4321 (cell) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential, proprietary and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender immediately and destroy or permanently delete all copies of the original message.