[phenixbb] Re: Seeking Advice on Difficult MR Case: TFZ 6–8 for All Search Models, R-free ~0.50

On 1 Jun 2026, at 08:51, [email protected] wrote:

I have collected a native dataset that extends to 2.45 Å resolution in space group P2₁2₁2 with unit-cell parameters approximately a = 46.9 Å, b = 91.9 Å, c = 165.0 Å.

Just to check - you have been trying MR in all 8 space groups compatible with P222 point group - i.e. P222, P222(1), P22(1)2, P2(1)22, P2(1)2(1)2, P2(1)22(1), P 22(1)2(1) and P2(1)2(1)2(1)? It's not uncommon for assignment of screw axes based on systematic absences to turn out to be incorrect. Huw