Hello Chris,
The standard question here is: Are you certain of your space group? That
seems to be the main culprit behind R factors that wont decrease.
Can you provide some statistics showing your confidence in your space group?
Kelly Daughtry
*******************************************************
Kelly Daughtry, Ph.D.
Post-Doctoral Fellow, Raetz Lab
Biochemistry Department
Duke University
Alex H. Sands, Jr. Building
303 Research Drive
RM 250
Durham, NC 27710
P: 919-684-5178
*******************************************************
On Wed, Jan 12, 2011 at 5:12 PM, Christopher W Davies
I am having an issue with refining my structure. I have a 2.36 A resolution dataset. I have found a solution by molecular replacement in the space group P3221. I have been refining the structure, however, my Rfactor/Rfree are not decreasing even though I have good density. My current Rfactor/Rfree values are .40/.43. Can anyone help me?
Thanks.
Chris _______________________________________________ phenixbb mailing list [email protected] http://phenix-online.org/mailman/listinfo/phenixbb