[phenixbb] Excellent Opportunity for Postdoc in Ion-Channel Structural Biology

Pramod Kumar pramodkbr at gmail.com
Fri Jan 7 16:13:09 PST 2022


Dear Structural Biology Scholars,



I would like to bring your attention to an excellent opportunity to unravel
the structure-function details of ion-channels as a postdoc. The Grosman
lab at the University of Illinois at Urbana-Champaign is actively looking to
fill a recent opening of NIH-funded postdoctoral position. The laboratory
has an excellent record in combining high-resolution electrophysiology,
molecular simulations, and structural biology to address fundamental
questions about ion-channel mechanisms. Previous experience with the
purification of eukaryotic membrane proteins is a plus and structure
determination using single-particle cryo-EM is highly preferred. Salary
commensurate with the experience level. The University of Illinois Urbana
Champaign is an excellent place for research and life with an easy commute,
lower-cost housing, easy access to all needs, and a vibrant community with
easily accessible cities like Chicago, Indianapolis, St. Louis.


Interested individuals should contact Prof. Claudio Grosman (
grosman at illinois.edu) with a CV, a 1–2 page description of previous
research, and names and contact information of 2–3 references. Students in
their final year of Ph.D. training are also welcome to apply.

Recent select publications from the Grosman lab are listed below. A
complete list of publications from the Grosman lab can be found on Prof.
Claudio Grosman’s NCBI bibliography page (
https://www.ncbi.nlm.nih.gov/myncbi/claudio.grosman.1/bibliography/public
<https://urldefense.com/v3/__https:/www.ncbi.nlm.nih.gov/myncbi/claudio.grosman.1/bibliography/public__;!!DZ3fjg!rQbPPU9HmgERY4wmiV22sCEFfhgBKyPAgmAjAc4NIwePpODucsYnvVtDcXV3NFUKog$>
).

*Recent Select Publications *

*· Kumar P, Cymes GD, Grosman C. Structure and function at the
lipid-protein interface of a pentameric ligand-gated ion channel. Proc.
Natl. Acad. Sci. USA. 2021;118(23). *

*doi: 10.1073/pnas.2100164118 *


*· Cymes GD, Grosman C. Signal transduction through Cys-loop receptors is
mediated by the nonspecific bumping of closely apposed domains. Proc. Natl.
Acad. Sci. USA. 2021;118(14). doi: 10.1073/pnas.2021016118 *




*doi: 10.1038/s41467-021-21680-9 *

*· Kumar P, Wang Y, Zhang Z, Zhao Z, Cymes GD, Tajkhorshid E, Grosman C.
Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel
embedded in a phosphatidylcholine-only bilayer. Proc. Natl. Acad. Sci. USA.
2020;117(3):1788-1798. *

*doi: 10.1073/pnas.1906823117 *



-- 

Pramod Kumar, Ph.D.
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