PHENIX is a software suite for the automated determination of molecular structures using X-ray
crystallography and other methods.|
Download the latest official release (1.16)
[First request download password]
Starting July 2019, the Protein Data Bank requires models to be in mmCIF for crystallographic structures.
You should use the latest official release (1.16) to generate these files for deposition.
Download the latest nightly build or prerelease|
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|Using PHENIX (release 1.16):
|- The PHENIX Graphical User Interface|
|- Assessing data quality with phenix.xtriage|
|- Automated structure solution with AutoSol|
|- Automated molecular replacement with Phaser-MR|
|- Automated model building and rebuilding with AutoBuild|
|- Automated ligand fitting with LigandFit|
|- Structure refinement with phenix.refine|
|- Generation of ligand coordinates and restraints with eLBOW|
The PHENIX system also includes SOLVE/RESOLVE, Phaser, the CCI Applications (phenix.xtriage, phenix.refine, elbow and many more), components from MolProbity, and the Computational Crystallography Toolbox in a Python
PHENIX: a comprehensive Python-based
system for macromolecular structure solution.
P. D. Adams, P. V. Afonine, G. Bunkóczi, V. B. Chen, I. W. Davis, N. Echols,
J. J. Headd, L.-W. Hung, G. J. Kapral, R. W. Grosse-Kunstleve, A. J. McCoy,
N. W. Moriarty, R. Oeffner, R. J. Read, D. C. Richardson, J. S. Richardson,
T. C. Terwilliger and P. H. Zwart.
Acta Cryst. D66, 213-221 (2010).
|Funding for PHENIX:
NIH General Medical Sciences
The PHENIX system also can be used for neutron crystallography. NIH funding supports the development of this capability through a grant to Paul Langan (Los Alamos National Laboratory) and Paul Adams. See the Macromolecular Neutron Crystallography Consortium site for more details. Citation for neutron structure refinement in Phenix: Adams PD, Mustyakimov M, Afonine PV, Langan P: Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules. Acta Cryst. 2009, D65:567-573.|